Thermo Fisher Scientific HSP90 alpha Monoclonal Antibody (M10E3R), APC

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

M10E3R

Immunogen

Purified HSP90 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HSP90 alpha,uniProtId:P07900-1,ncbiNodeId:9606,antigenRange:1-732,antigenLength:732,antigenImageFileName:MA5-45087_HSP90_alpha_P07900-1_House_mouse.svg,antigenImageFileNamePDP:MA5-45087_HSP90_alpha_P07900-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

APC APC APC

View additional formats

• FITC
• PerCP
• Request custom conjugation

Excitation/Emission Max

651/660 nm View spectra

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

47.35mM phosphate/2.15mM MES, pH 7.4, with 1.033mM EDTA

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2931541

Product Specific Information

A 1:1,000 dilution of MA5-45087 was sufficient for detection of HSP90a in 10 µg of HeLa by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.|Detects 90 kDa. Does not detect HSP90 beta.

Target Information

Heat shock proteins (HSP) are proteins that are expressed in response to various biological stress, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, and some kinases. It has been suggested that HSP90 is necessary to maintain structural integrity of at least some steroid receptors to allow for ligand binding during receptor activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.