Thermo Fisher Scientific Rab5 (RAB5A) Monoclonal Antibody (OTI6D9)
Rab5 (RAB5A) 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Human, Mouse, Rat에 반응합니다. Western blot에 최적화되어 있으며, 동결건조 형태로 제공됩니다. 세포 내 막수송 및 엔도솜 융합 연구에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D9 |
| Immunogen | Full length human recombinant protein of human RAB5A (NP_004153) produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
RAB5 proteins are small GTPases that regulate intracellular membrane trafficking, including vesicle formation and membrane fusion.
RAB5A is essential for plasma membrane and early endosome fusion, regulates filopodia extension, and is required for exosomal release of SDCBP, CD63, PDCD6IP, and syndecan.
It also plays a role in the maturation of apoptotic cell-containing phagosomes, acting downstream of DYN2 and PIK3C3.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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