Thermo Fisher Scientific MSF (SEPT9) Monoclonal Antibody (OTI2B12)

Thermo Fisher Scientific MSF (SEPT9) Monoclonal Antibody (OTI2B12)

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses:

• Large Mafs: vMaf, cMaf, MafB, and Nrl
• Small Mafs: MafF, MafK, and MafG

Both subclasses contain leucine zipper motifs, enabling homo- and heterodimerization with other bZip transcription factors.
Large Mafs have an acidic transactivation domain, while small Mafs lack this domain but can regulate transcription positively or negatively depending on their dimerization partners.

Human MafF was isolated from a human myometrium cDNA library and encodes a 164 amino acid protein. Like other small Maf proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivation domain.
Small Maf proteins are involved in development, differentiation, hematopoiesis, and stress response, regulating transcription through multiple mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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