Thermo Fisher Scientific MSF (SEPT9) Monoclonal Antibody (OTI3G2)

Applications

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The Maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family includes large Mafs (vMaf, cMaf, MafB, Nrl) and small Mafs (MafF, MafK, MafG). Both subclasses contain leucine zipper motifs allowing homo- and heterodimerization with other bZip transcription factors.
Large Mafs have an acidic transactivation domain absent in small Mafs. Small Maf proteins can act as positive or negative regulators of transcription by interacting with transcriptional partners or repressors.
Human MafF, a small Maf protein, encodes a 164 amino acid protein with an extended leucine zipper and no N-terminal transactivation domain. These small Maf proteins are involved in development, differentiation, hematopoiesis, and stress response, each via distinct mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.