Thermo Fisher Scientific CD98 Monoclonal Antibody (MEM-108)
인간 CD98 단백질을 인식하는 Mouse IgG1 단일클론 항체로 IHC, Flow Cytometry, Immunoprecipitation에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며 Protein A로 정제됨. 4°C 보관, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
| Flow Cytometry (Flow) | 4 µg/mL |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-108 |
| Immunogen | Burkitt's lymphoma cell line Raji |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073517 |
Available Conjugated Formats
Product Specific Information
This antibody reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glycosylated light chain). CD98 is expressed on activated T lymphocytes and NK cells, and at low levels on B lymphocytes, monocytes, and platelets.
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein serving as the heavy chain of heterodimeric amino acid transporters (HATs). It interacts with various light chains by disulfide bonds, enabling cell surface expression and basolateral localization in epithelial cells. CD98 also interacts with β1 integrins, enhancing ligand affinity, and is involved in cell fusion, activation, differentiation, growth, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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