Thermo Fisher Scientific GPX3 Monoclonal Antibody (23B1)
Thermo Fisher Scientific의 GPX3 Monoclonal Antibody (23B1)은 인간 GPX3 단백질을 인식하는 Mouse IgG1 단클론 항체입니다. Western blot에 적합하며, 비결합(Unconjugated) 형태로 제공됩니다. 연구용으로만 사용 가능하며, -20°C에서 보관해야 합니다.
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Thermo Fisher Scientific GPX3 Monoclonal Antibody (23B1)
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Publications: - References
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 23B1 |
| Immunogen | Purified, His-tagged, recombinant, human glutathione peroxidase 3 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2112275 |
Product Specific Information
A suggested positive control for this product is Bosc23 cells transfected with myc-Gpx3.
Target Information
Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins that catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione.
There are several isoforms differing in primary structure and localization:
- GPx1 (cGPx): Classical cytosolic/mitochondrial, selenium-dependent enzyme.
- GPx2 (GI-GPx): Expressed in gastrointestinal epithelium.
- GPx3 (pGPx): Extracellular plasma form, mainly expressed by kidney and released into blood circulation.
- GPx4 (PH-GPx): Reduces hydroperoxides in membranes and lipoproteins.
All mammalian GPx family members, except the Cys-containing GPx3 and epididymis-specific GPx5, possess selenocysteine at the active site.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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