Thermo Fisher Scientific PON1 Monoclonal Antibody (17A12)
Thermo Fisher Scientific의 PON1 단클론 항체(17A12)는 인간 PON1 단백질을 인식하는 Mouse IgG1 형 항체로, Western blot에 적합합니다. HepG2 세포를 양성 대조군으로 사용 권장되며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 2–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 17A12 |
| Immunogen | Purified, His-tagged, recombinant, human PON1 protein expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2166313 |
Product Specific Information
A suggested positive control for this product is HepG2 cells.
Target Information
The paraoxonase (PON) gene family in humans includes PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is synthesized primarily in the liver and secreted into plasma, where it associates with HDL.
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism may contribute to neurodegeneration and is considered an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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