Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (8C12)
SERPINC1 단백질(안티트롬빈 III)을 인식하는 Thermo Fisher Scientific의 Mouse IgG1 단클론 항체입니다. Western blot 및 ELISA에 사용 가능하며, 인간 혈장 유래 단백질을 면역원으로 제작되었습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific SERPINC1 Monoclonal Antibody (8C12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8C12 |
| Immunogen | Antithrombin III protein purified from human plasma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1070423 |
Product Specific Information
A suggested positive control for this product is human plasma.
Target Information
The protein encoded by SERPINC1 is a plasma protease inhibitor and a member of the serpin superfamily.
It inhibits thrombin and other activated serine proteases of the coagulation system, regulating the blood coagulation cascade.
The protein contains two functional domains:
- Heparin binding domain at the N-terminus of the mature protein
- Reactive site domain at the C-terminus
Its inhibitory activity is enhanced by the presence of heparin.
More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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