Thermo Fisher Scientific Phospho-Paxillin (Tyr31) Polyclonal Antibody
Phospho-Paxillin (Tyr31) 특이적 폴리클로날 항체로 인간 및 마우스 반응성 검증됨. Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 친화 크로마토그래피로 정제된 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 21 publications |
| Immunohistochemistry (IHC) | Assay-dependent | View 4 publications |
| Immunocytochemistry (ICC/IF) | 1:250 | View 12 publications |
| Immunoprecipitation (IP) | – | View 1 publication |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse, Pig, Rat, Tag |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human paxillin that contains tyrosine 31. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.3, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533732 |
Target Information
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as Src, FAK, and p210BRC/ABL. Tyrosine phosphorylation of paxillin is influenced by conditions that alter cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain, independently of the extracellular matrix. Although initially discovered in fibroblasts, its phosphorylation may also play a role in neurite extension during differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: 44-720G_Paxillin_P49023-1_Rabbit.svg, 44-720G_Paxillin_P49023-1_Rabbit_PDP.jpeg)
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