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Thermo Fisher Scientific Phospho-Tau (Thr212) Polyclonal Antibody

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Tau 단백질 Thr212 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, ICC/IF 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 인간, 마우스, 랫 등에서 반응.

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마지막 업데이트 2026. 08. 13. 오전 10:20

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Thermo Fisher Scientific 44740G Phospho-Tau (Thr212) Polyclonal Antibody 100 ul pk판매 단위 pk ·

재고 확인 필요재고 확인 필요

616,900원VAT 포함 678,590원

재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Application	Tested Dilution	Publications
Western Blot (WB)	1:1,000	25 publications
Immunohistochemistry (IHC)	-	2 publications
Immunohistochemistry (Paraffin) (IHC (P))	-	1 publication
Immunocytochemistry (ICC/IF)	1 µg/mL	1 publication
ELISA	-	2 publications
Dot blot (DB)	-	1 publication
Miscellaneous PubMed (Misc)	-	1 publication

항목	내용
Species Reactivity	Human, Mouse, Rat
Published Species	Baboon, Bovine, Dog, Human, Mouse, Non-human primate, Rat, Sheep, Tag
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Chemically synthesized phosphopeptide derived from human Tau region containing threonine 212. Sequence conserved in mouse, rat, rhesus monkey, baboon, cow, and goat.
Conjugate	Unconjugated
Form	Liquid
Purification	Antigen affinity chromatography
Storage Buffer	Dulbecco’s PBS, pH 7.3, with 1 mg/mL BSA
Contains	0.05% sodium azide
Storage Conditions	-20°C
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_2533739

Purified from rabbit serum by sequential epitope-specific chromatography.
Contains enough material for 10 mini-blots.
Negatively preadsorbed using a non-phosphopeptide to remove non-phosphorylated Tau-reactive antibodies.
Final product generated by affinity chromatography using Tau peptide phosphorylated at threonine 212 (isoform Tau 441).
Positive control for western analysis: recombinant human Tau +/- GSK-3β.

Tau is a neuronal microtubule-associated protein primarily located on axons. It promotes tubulin polymerization and stabilizes microtubules.

C-terminus binds axonal microtubules; N-terminus binds neural plasma membrane components.
Functions as a linker between cytoskeleton and membrane.
Hyper-phosphorylated Tau forms paired helical filaments (PHF), a major component of neurofibrillary tangles in Alzheimer’s disease.
Hyper-phosphorylation impairs microtubule binding, leading to neuronal degeneration.
Phosphorylation by kinases: GSK-3β, PKA, cdk5, casein kinase II.
Found in neurodegenerative diseases including Pick’s disease, frontotemporal dementia, corticobasal degeneration, and progressive supranuclear palsy.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

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