Thermo Fisher Scientific PPAR gamma 2 Polyclonal Antibody
Human 및 Rhesus monkey에 반응하는 PPAR gamma 2 폴리클로날 항체로, Western blot, ELISA, Immunoprecipitation에 사용 가능. Affinity chromatography로 정제된 비결합형 액상 항체이며, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific PPAR gamma 2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:4,000–1:40,000 |
| Immunoprecipitation (IP) | 1:1,000–1:3,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rhesus monkey |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region near the amino terminus of human PPAR gamma 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid cycles of freezing and thawing.
- Centrifuge product if not completely clear after standing at room temperature.
- Stable for several weeks at 4°C as an undiluted liquid.
- Dilute only prior to immediate use.
This affinity purified antibody is directed against human PPAR gamma isoform 2 protein.
BLAST analysis suggests reactivity with human and macaque proteins based on 100% homology for the immunogen sequence.
Cross-reactivity with dog and swine PPARγ2 (94% homology) and mouse PPARγ2 (87% homology) is likely.
No reactivity is expected against other subtypes of PPAR.
Target Information
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors.
PPARs form heterodimers with retinoid X receptors (RXRs) and regulate transcription of various genes.
Three subtypes are known: PPAR-alpha, PPAR-delta, and PPAR-gamma.
PPAR-gamma regulates adipocyte differentiation and is implicated in obesity, diabetes, atherosclerosis, and cancer.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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