Thermo Fisher Scientific Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT6/8198R)
Basal cell marker로 사용되는 Cytokeratin 6 (KRT6) 인식 항체. 인간 시료에 반응하며, IHC(P) 및 IHC(PFA)에서 검증됨. Recombinant Rabbit Monoclonal 형식으로 높은 특이성과 재현성 제공. 4°C 보관, Protein A/G 정제.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT6/8198R |
| Immunogen | Recombinant fragment (around aa1–200) of human KRT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region (hyperproliferation-related keratins).
Keratin 6 is found in hair follicles and suprabasal cells of various internal stratified epithelia, including epidermis, under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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