Thermo Fisher Scientific Fibrinogen Polyclonal Antibody
Human fibrinogen을 인식하는 Chicken IgY 폴리클로날 항체로 Western blot, ELISA 등에 사용 가능. 비결합형 액상 형태로 제공되며, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific Fibrinogen Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| ELISA | 1:1,000–1:5,000 | 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mixture of synthetic peptides based on human fibrinogen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | IgY fraction |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2103482 |
Product Specific Information
PA1-9526 detects Fibrinogen in human samples.
It has been successfully used in Western blot and ELISA procedures.
By Western blot, PA1-9526 detects a ~94 kDa protein representing Fibrinogen.
The immunogen is a mixture of synthetic peptides based on human fibrinogen.
Target Information
Fibrinogen is the precursor of fibrin, the coagulable protein in vertebrate plasma.
Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots.
Fibrinogen consists of a dimer of three pairs of non-identical chains (FGA, FGB, FGG) cross-linked by disulfide bonds in their N-terminal regions.
The molecule has two terminal D domains and one central E domain, which are separated when degraded by plasmin.
Mutations in this gene can lead to disorders such as dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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