Thermo Fisher Scientific MSI2 Polyclonal Antibody
MSI2 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태이며 1 mg/mL 농도.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the amino terminus of human MSI2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152617 |
Product Specific Information
- Suggested positive control: EL4 cell lysate
- PA5-21145 can be used with blocking peptide PEP-1259.
Target Information
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. It is expressed ubiquitously at low levels and functions as an RNA-binding protein that regulates the expression of target mRNAs. Msi2 plays a role in the proliferation and maintenance of stem cells within the central nervous system. It is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting involvement in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.
Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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