Thermo Fisher Scientific ORMDL1 Polyclonal Antibody
Thermo Fisher Scientific ORMDL1 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 항체입니다. Western blot 및 IHC에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. Alzheimer’s disease 및 천식 관련 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide of human ORMDL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153467 |
Product Specific Information
- Suggested positive control: SK-N-SH cell lysate
- PA5-21146 can be used with blocking peptide PEP-1260
Target Information
The ORMDL (ORM1-like) family of proteins, including ORMDL1, ORMDL2, and ORMDL3, may play roles in γ-secretase complex maturation. These proteins are localized to the endoplasmic reticulum membrane and are widely expressed. ORMDLs are implicated in the expression of Presenilin (PSI), which is involved in Alzheimer’s disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a potential role as a therapeutic target for AD. Additionally, ORMDLs have been identified as a potential risk factor for childhood asthma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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