Thermo Fisher Scientific IRF4 Polyclonal Antibody
IRF4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 시료에 반응하며 WB 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5 µg/mL
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human IRF4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152871 |
Product Specific Information
- A suggested positive control is Jurkat cell lysate.
- PA5-21144 can be used with blocking peptide PEP-1258.
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain.
IRFs regulate interferons in response to viral infection and control interferon-inducible genes.
IRF4 is lymphocyte-specific and negatively regulates TLR signaling, which is central to innate and adaptive immune activation.
A chromosomal translocation involving IRF4 and IgH locus, t(6;14)(p25;q32), may cause multiple myeloma.
Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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