Thermo Fisher Scientific CD26 Monoclonal Antibody (ICO-147)

Applications and Tested Dilution

Product Specifications

Product Specific Information

• MA1-7651 detects CD26 from human samples.
• Successfully used in Immunoprecipitation and ELISA assays.
• The immunogen consists of activated T, B lymphocytes, and macrophages.

Target Information

CD26 (dipeptidyl peptidase IV, DPP IV; adenosine deaminase binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
It is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, natural killer cells, and epithelial tissues.

CD26 participates in:

• T-cell activation and adhesion to extracellular matrix (e.g., fibronectin, collagens)
• HIV infection processes
• Regulation of enzymatic activity linked to malignant transformation and tumor progression

Altered CD26 expression or activity is associated with autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.