
Thermo Fisher Scientific CD26 Monoclonal Antibody (ICO-147)
CD26 단백질을 인식하는 인간 반응성 마우스 단클론 항체. ELISA 및 면역침전(IP) 실험에 적합하며, Protein A로 정제된 1 mg/mL 액상 제품. 활성화된 T, B 림프구 및 대식세포 유래 항원을 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICO-147 |
| Immunogen | Activated T, B lymphocytes and macrophages |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2 |
| Contains | No preservative |
| Storage conditions | 4°C short term, -80°C long term |
| RRID | AB_1071815 |
Product Specific Information
- MA1-7651 detects CD26 from human samples.
- Successfully used in Immunoprecipitation and ELISA assays.
- The immunogen consists of activated T, B lymphocytes, and macrophages.
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV; adenosine deaminase binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
It is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, natural killer cells, and epithelial tissues.
CD26 participates in:
- T-cell activation and adhesion to extracellular matrix (e.g., fibronectin, collagens)
- HIV infection processes
- Regulation of enzymatic activity linked to malignant transformation and tumor progression
Altered CD26 expression or activity is associated with autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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