Thermo Fisher Scientific CD34 Monoclonal Antibody (ICO-115)
인간 CD34 단백질을 인식하는 마우스 단클론 항체로, IHC 및 유세포분석에 적합. 비결합형 액상 형태로 제공되며, 단백질 A로 정제됨. 줄기세포 표지자로 활용 가능하며 연구용으로 사용.
- 카탈로그번호
- MA17652
- 판매단위
- pk
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:1,000
Flow Cytometry (Flow)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ICO-115 |
| Immunogen | Hematopoietic precursor cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.01% sodium azide |
| Storage Conditions | 4°C short term, -80°C long term |
| RRID | AB_1072167 |
Product Specific Information
- MA1-7652 detects CD34 from human samples.
- Successfully used in flow cytometry procedures.
- Immunogen: Hematopoietic precursor cells.
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) expressed on many stem cell populations. It serves as a stem cell marker and may function as a surface receptor involved in adhesion, differentiation, and proliferation of hematopoietic stem cells and progenitors. CD34 expression represents a specific developmental state and may influence stem cell attachment to the bone marrow extracellular matrix or stromal cells. It may also act as a scaffold for glycan attachment and participate in selectin-mediated interactions. Phosphorylation by protein kinase C suggests a possible role in signal transduction.
Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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