Thermo Fisher Scientific AMACR Monoclonal Antibody (OTI2A11), TrueMAB
AMACR 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 IHC(Paraffin)에 적합합니다. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 재구성 용이합니다. 인간 시료에 반응하며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A11 |
| Immunogen | Full length human recombinant protein of human AMACR produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme in the β-oxidation of branched-chain fatty acids.
High expression of P504S protein is observed in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining of paraffin-embedded tissue.
Expression is also detected in two premalignant prostate lesions: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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