Thermo Fisher Scientific HOXD10 Monoclonal Antibody (OTI1F7), TrueMAB

Applications

• Western Blot (WB): Tested at 1:2,000 dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The HOXD10 gene belongs to the Abd-B homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain.
It is part of the homeobox D gene cluster located on chromosome 2.
This transcription factor is expressed in developing limb buds and plays a role in differentiation and limb development.
Mutations have been linked to Wilms' tumor and congenital vertical talus, as well as foot deformities resembling those in Charcot-Marie-Tooth disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.