Thermo Fisher Scientific GLB1L3 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:100

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total GLB1L3 protein.

Target Information

GLB1L3 (beta-galactosidase-1-like protein 3) is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25.
Chromosome 11 comprises approximately 135 million base pairs and 1,400 genes, representing about 4% of the human genome. It is considered gene- and disease-association dense.
The chromosome 11–encoded Atm gene regulates cell cycle arrest and apoptosis following double-strand DNA breaks. Atm mutation leads to ataxia-telangiectasia. Other disorders associated with chromosome 11 defects include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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