Thermo Fisher Scientific CaMKII beta/gamma Polyclonal Antibody
CaMKII beta/gamma 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ICC/IF에 적합합니다. 인간, 생쥐, 랫트에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 단기, -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (IHC) | 1:50–1:200 | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 601–652 of human CaMKII beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553410 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 50–80 kDa.
- Purity >95% by SDS-PAGE.
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases including CaMKI, CaMKII, and CaMKIV.
CaMKII is a ubiquitously expressed serine/threonine protein kinase activated by Ca²⁺ and calmodulin (CaM), implicated in regulation of the cell cycle and transcription.
There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may or may not be coexpressed in the same tissue type.
CaMKIV is stimulated by Ca²⁺ and CaM but also requires phosphorylation by a CaMK for full activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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