Thermo Fisher Scientific ZNF174 Polyclonal Antibody
ZNF174 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(Paraffin) 분석에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 168–228 of human ZNF174 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553414 |
Product Specific Information
- Detects endogenous ZNF174 protein with a molecular weight of approximately 46 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
ZNF174 (also known as ZSCAN8 or AW-1) is a transcriptional repressor belonging to the Krueppel C2H2-type zinc-finger protein family. It is expressed in various tissues including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney, and thymus, with predominant expression in adult ovary and testis.
ZNF174 represses promoter activities of PDGF-B and TGF beta1, localizes to the nucleus, and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. The SCAN domain facilitates noncovalent complex formation and selective oligomerization among SCAN domain-containing proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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