Thermo Fisher Scientific SS18 Polyclonal Antibody
인간, 마우스, 랫트 반응성의 Rabbit Polyclonal 항체로, SYT 단백질의 N-말단 합성 펩타이드에 대해 제작되었습니다. IHC(P)에서 1:50–1:200 희석으로 사용 가능하며, 45 kDa의 내인성 단백질을 검출합니다. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상입니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminal of human SYT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2553412 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 45 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which functions as a transcriptional activating sequence.
Synovial sarcoma translocation (SSX) proteins, including SSX1–5, are transcriptional repressors that contain a repressor domain in their carboxy termini.
SSX proteins are localized to the nucleus and expressed in testis and several types of cancers, and are therefore classified as C/T (cancer/testis) antigens.
The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2, producing transcriptional activators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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