Thermo Fisher Scientific SEMA3F Polyclonal Antibody
SEMA3F 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체입니다. Western blot에 최적화되어 있으며 인간, 마우스, 랫트 시료에 반응합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며 안정적인 PBS/BSA/glycerol 버퍼에 보존됩니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:100
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Semaphorin 3F synthetic peptide (coupled to carrier protein) corresponds to amino acids from the C-terminal region of human Sema-3F. This sequence is highly conserved in rat and mouse Sema-3F, and has low homology to other semaphorin family members. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2942988 |
Product Specific Information
The antibody detects a 95 kDa* protein corresponding to the apparent molecular mass of Sema-3F on SDS-PAGE immunoblots of adult mouse brain and liver.
Target Information
The semaphorins are a family of proteins involved in signaling. All family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993 [PubMed 8269517]).
Sequence comparisons have grouped the secreted semaphorins into three general classes, all of which also have an immunoglobulin domain.
The semaphorin III family—including human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E—all have a basic domain at the C terminus.
Chicken collapsin contributes to pathfinding by axons during development by inhibiting growth cone extension (Luo et al., 1993 [PubMed 8402908]) through interaction with a collapsin response mediator protein (CRMP62) (Goshima et al., 1995 [PubMed 7637782]), a homolog of the UNC33 gene product (MIM 601168).
SEMA3F is a secreted member of the semaphorin III family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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