Thermo Fisher Scientific SPACA3 Polyclonal Antibody
SPACA3 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. Western Blot, ELISA, Immunoprecipitation 등에 적합. 고순도 Affinity chromatography 정제, 안정적인 액상 형태로 연구용에 최적화.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides within amino acid region 80–130 of human sperm acrosome membrane-associated protein 3 isoform 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPACA3 (Sperm Acrosome Associated 3), also known as sperm lysozyme-like protein 1 or LYZL3, is a 215 amino acid protein involved in sperm–egg plasma membrane adhesion and fusion during fertilization. It is identified as a cancer/testis antigen capable of eliciting B-cell immune responses in cancer patients, making it a potential immunotherapy target.
SPACA3 belongs to the glycosyl hydrolase 22 family and is expressed in testis, placenta, and epididymis. Isoform 1 is a membrane protein of the sperm acrosome, while isoform 2 is secreted. The processed form lacks bacteriolytic activity in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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