Thermo Fisher Scientific Phospho-VEGF Receptor 2 (Tyr951) Polyclonal Antibody
VEGFR2 Tyr951 인산화 상태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 사용 가능하며 Human, Mouse, Rat 반응성. 고순도 정제, 액상 형태로 안정적이며 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KDR (Accession P35968), corresponding to amino acid residues around phosphorylated Tyr951 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2816355 |
Product Specific Information
Antibody detects endogenous levels of VEGFR2 only when phosphorylated at Tyrosine 951.
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor with high affinity in vitro. It is expressed early in development by endothelial cell precursors.
FLK1 (VEGF Receptor 2) encodes one of the two receptors of VEGF, known as kinase insert domain receptor.
The signaling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase.
Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-104882_FLK1_VEGF_Receptor_2_P35968-1_Rabbit.svg, PA5-104882_FLK1_VEGF_Receptor_2_P35968-1_Rabbit_PDP.jpeg)
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