Thermo Fisher Scientific Lamin B1 Polyclonal Antibody
Thermo Fisher Scientific Lamin B1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 폴리클로날 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | View 22 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.1–1.0 µg/mL | View publications |
| Immunocytochemistry (ICC/IF) | 0.1 µg/mL | View 4 publications |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 400–500 of Mouse Lamin B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985414 |
Product Specific Information
- Heat-mediated antigen retrieval recommended prior to tissue staining.
- This antibody is predicted to react with chicken and zebrafish based on sequence homology.
Target Information
Laminins are extracellular matrix glycoproteins and major noncollagenous constituents of basement membranes. They play roles in cell adhesion, differentiation, migration, signaling, neurite outgrowth, and metastasis. Laminins consist of three non-identical chains (alpha, beta, gamma), forming a cruciform structure.
Defects in the LMNB1 gene can cause Leukodystrophy, demyelinating, autosomal dominant, adult-onset (ADLD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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