Thermo Fisher Scientific BCL2A1 Recombinant Rabbit Monoclonal Antibody (SC05-42)
BCL2A1 단백질을 인식하는 Thermo Fisher의 SC05-42 재조합 토끼 모노클로날 항체. Western blot, IHC, Flow cytometry에 적합하며 높은 특이성과 일관된 로트 간 재현성을 제공. HEK293 발현 시스템 기반, 단백질 A 정제, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC05-42 |
| Immunogen | Synthetic peptide within Human BCL2A1 aa 2–48 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809486 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal clones for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Bcl-2 related Protein A1 is a member of the BCL-2 protein family, which regulates apoptosis through hetero- or homodimer formation. It reduces the release of pro-apoptotic cytochrome c from mitochondria and blocks caspase activation.
This gene is a direct transcriptional target of NF-kappa B and is upregulated by signals such as GM-CSF, CD40, phorbol ester, TNF, and IL-1, contributing to cytoprotective functions essential for lymphocyte activation and cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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