Thermo Fisher Scientific Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody (SC52-09)
Cytokeratin 16에 특이적인 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 높은 특이성과 민감도, 일관된 로트 간 품질, 동물 유래 성분 없음. 연구용으로 4°C 단기 보관, 장기 보관 시 -20°C 권장.
- 판매단위
- pk
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Thermo Fisher Scientific Cytokeratin 16 Recombinant Rabbit Monoclonal Antibody (SC52-09)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC52-09 |
| Immunogen | Synthetic peptide within human Cytokeratin 16 (aa 27–75) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809483 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal clones for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
KRT16 is a member of the keratin gene family, encoding intermediate filament proteins that maintain epithelial cell structural integrity.
Type I cytokeratins are acidic proteins paired with heterotypic keratin chains, clustered on chromosome 17q12–q21.
KRT16 is coexpressed with keratin 14 in epithelial tissues such as esophagus, tongue, and hair follicles.
Mutations in KRT16 are associated with:
- Type 1 pachyonychia congenita
- Non-epidermolytic palmoplantar keratoderma
- Unilateral palmoplantar verrucous nevus
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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