Thermo Fisher Scientific FOS Monoclonal Antibody (OTI3B8), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates genes involved in cellular signal transduction, proliferation, and differentiation.
c-Fos is phosphorylated by various stimuli, including growth factors and insulin, at multiple sites. The ERK MAPK kinase phosphorylates Threonine 232, influencing nuclear localization and transcriptional activity of c-Fos.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.