Thermo Fisher Scientific Complement C5a Monoclonal Antibody (C17/5)
인체 및 비인간 영장류 C5a 단백질을 인식하는 단클론 항체로, ELISA 및 Western blot에 적합. 비접합형 액상 형태로 제공되며 Protein A로 정제됨. PBS 버퍼와 sodium azide 포함, 4°C 암소 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Complement C5a Monoclonal Antibody (C17/5)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | - |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C17/5 |
| Immunogen | Purified human C5a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL (lot-dependent, 0.85–1.15 mg/mL) |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536531 |
Product Specific Information
- Specificity: GAU 025-05 reacts with human C5a/C5a (desArg) and cross-reacts with baboon C5a/C5a (desArg).
- Reactivity: In ELISA, recombinant C5a coated onto a microtiter well results in a strong reaction.
- Note: Concentration may vary by lot (0.85–1.15 mg/mL).
Target Information
The protein encoded by this gene is the fifth component of complement, playing an important role in inflammatory and cell-killing processes. It consists of alpha and beta polypeptide chains linked by a disulfide bridge. The activation peptide C5a, an anaphylatoxin with spasmogenic and chemotactic activity, is derived from the alpha chain via cleavage with a convertase. The C5b product forms a complex with C6, initiating formation of the membrane attack complex. Mutations in this gene cause complement component 5 deficiency, associated with recurrent infections, and have been linked to liver fibrosis and rheumatoid arthritis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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