Thermo Fisher Scientific ZRANB2 Monoclonal Antibody (OTI2E3), TrueMAB

Applications

• Western Blot (WB): Assay-dependent
• Immunohistochemistry (Paraffin) (IHC (P)): 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Zinc-finger proteins contain DNA-binding domains and perform diverse functions, primarily involving transcriptional activation or repression.
ZRANB2 (also known as ZNF265, ZIS, ZIS1, or ZIS2) is a 330-amino-acid nuclear protein functioning as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts. It contains two RanBP2-type zinc fingers that mediate RNA-binding activity. Two isoforms, ZIS-1 and ZIS-2, arise from alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.