Thermo Fisher Scientific ZRANB2 Monoclonal Antibody (OTI2E3), TrueMAB
Human ZRANB2 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(P)에서 검증됨. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. PBS(pH 7.3) 및 8% 트레할로스 함유, 보존제 없음. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 95–320 of human ZRANB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Zinc-finger proteins contain DNA-binding domains and perform diverse functions, primarily involving transcriptional activation or repression.
ZRANB2 (also known as ZNF265, ZIS, ZIS1, or ZIS2) is a 330-amino-acid nuclear protein functioning as a splicing factor responsible for alternative splicing of Tra-2 beta transcripts. It contains two RanBP2-type zinc fingers that mediate RNA-binding activity. Two isoforms, ZIS-1 and ZIS-2, arise from alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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