Thermo Fisher Scientific TK1 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal TK1 항체. Western blot과 IHC(Paraffin)에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품. PBS/glycerol buffer에 보존되며 4℃ 또는 -20℃에서 안정적으로 저장 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–223 of Human Thymidine Kinase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547160 |
Product Specific Information
- Recommended positive controls: A431, A431 cytoplasm extract
- Predicted reactivity: Mouse (91%), Rat (91%), Zebrafish (81%), Chicken (83%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells.
It catalyzes the reaction:
deoxythymidine + ATP → deoxythymidine 5′-phosphate + ADP,
which is essential for DNA synthesis.
TK1 is required for the action of several antiviral drugs (e.g., AZT) and is used in hybridoma cell line selection during monoclonal antibody production.
Clinically, TK1 serves as a marker associated with cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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