Thermo Fisher Scientific TIA-1 Polyclonal Antibody

Thermo Fisher Scientific TIA-1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A549, 293T, A431, HeLa, HepG2, Molt-4
• Predicted reactivity: Mouse (100%), Rat (90%), Zebrafish (83%), Xenopus laevis (88%), Chicken (89%), Rhesus Monkey (100%), Bovine (99%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through signals from:

1. WNT3A protein, stabilizing beta-catenin
2. Noggin, a bone morphogenetic protein inhibitor

Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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