Thermo Fisher Scientific UNC5D Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant human UNC5H4 Gly15-Ser373 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UNC5D,uniProtId:Q6UXZ4-1,ncbiNodeId:9606,antigenRange:15-373,antigenLength:953,antigenImageFileName:PA5-47137_UNC5D_Q6UXZ4-1_Goat.svg,antigenImageFileNamePDP:PA5-47137_UNC5D_Q6UXZ4-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2607189

Product Specific Information

Less than 5% cross-reactivity with recombinant rat (rr) UNC5H1, rrUNC5H2, and recombinant human UNC5H3 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.