Thermo Fisher Scientific P2X7 Receptor (extracellular) Polyclonal Antibody, PE

Applications

• Flow Cytometry (Flow): Tested at 2.5 µg

Product Specifications

Product Specific Information

• Reconstitution: Add 15 µL or 50 µL of double distilled water (DDW), depending on sample size.
• Ships as lyophilized powder at room temperature.
• Upon arrival, store at -20°C.
• Reconstituted solution: store at 4°C, protected from light, up to 1 week.
• For long-term storage, aliquot and freeze at -20°C.
• Avoid multiple freeze-thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

The P2X7 receptor belongs to the purinoceptor family for ATP. It functions as a ligand-gated ion channel responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this receptor by ATP may couple cellular activity to gene expression changes. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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