
Thermo Fisher Scientific P2Y1 Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting P2Y1 receptor for WB and IHC applications. Reacts with human, mouse, and rat. Lyophilized form purified by antigen affinity chromatography. Ideal for platelet and neuronal signaling research.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)RALI YKDLD NSPLR RKS, corresponding to residues 242–258 of rat or human P2RY1. Located in the 3rd intracellular loop (i3) between TM5 and TM6 domains. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week. For longer storage, aliquot and store at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
P2Y1 is a purinergic receptor that induces platelet shape change and aggregation through ADP binding, activating phospholipase C and mobilizing intracellular calcium ions.
It mediates nitric oxide release and may modulate neuronal signal transmission.
P2Y1 is expressed in various tissues, especially the brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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