Thermo Fisher Scientific Phospho-Cdc25C (Ser216) Monoclonal Antibody (K.827.0)
Phospho-Cdc25C (Ser216) 단백질을 인식하는 Rabbit monoclonal 항체입니다. Western blot, IHC, IP에 사용 가능하며, 인산화된 Cdc25C의 세포주기 조절 연구에 적합합니다. 고순도, 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K.827.0 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer216 of human Cdc25C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 170 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_11000618 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved and plays a key role in cell division regulation. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family. It dephosphorylates cyclin B-bound CDC2 (CDK1), triggering entry into mitosis and may suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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