Thermo Fisher Scientific Histone H3 Monoclonal Antibody (E.960.2)
Western blot에 최적화된 Rabbit monoclonal 항체로, 인간 및 다양한 종의 Histone H3 단백질을 검출합니다. 핵심 히스톤 단백질에 특이적으로 반응하며 교차 반응이 없습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Publications: View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Fruit fly, Hamster, Human, Mouse, Non-human primate, Pig, Rat, Zebrafish |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.960.2 |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminal residues of human histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 21 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10985076 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other core histones.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it binds DNA to form the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, replication, and chromosomal stability.
The N-terminal tail of histone H3 can undergo various post-translational modifications, including methylation, acetylation, and phosphorylation, which regulate chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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