Thermo Fisher Scientific Phospho-VEGF Receptor 2 (Tyr951) Monoclonal Antibody (H.266.3)
VEGFR2의 Tyr951 인산화 부위를 인식하는 단클론 항체로 인간 및 생쥐 시료에 반응합니다. Western blot 및 면역세포염색에 사용 가능하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | H.266.3 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr951 of human VEGF receptor 2 (target family: FLK1 (VEGF Receptor 2), UniProt ID: P35968-1, antigen range: 951–1356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10982109 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor (VEGF) with high affinity in vitro. It is expressed early in development by endothelial cell precursors.
FLK1 (VEGF Receptor 2) encodes one of the two receptors for VEGF, known as the kinase insert domain receptor. The signaling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase.
Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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