Thermo Fisher Scientific SLC9A1 Polyclonal Antibody
SLC9A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC 실험에 사용 가능. 인간 시료 반응성이 있으며, PBS buffer에 보관. 장기 보관 시 -20°C에서 냉동 보관 권장. 연구용으로만 사용.
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Thermo Fisher Scientific SLC9A1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 5 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from cytoplasmic domain of Sodium / Hydrogen Exchanger 1 (SLC9A1, NHE1) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SLC9A1.
Target Information
The Na⁺/H⁺ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by various signals including growth factors, mitogens, neurotransmitters, and tumor promoters.
Nhe-1 acts as an anchor for actin filaments to maintain the integrity of the cortical cytoskeleton through structural links with actin-binding proteins such as ezrin, radixin, and moesin (ERM proteins).
A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton independent of its ion exchange function. It may also play a role in hypertension. At least two isoforms of Nhe-1 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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