Thermo Fisher Scientific SLC9A1 Polyclonal Antibody
SLC9A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간 시료에 반응하며, 합성 펩타이드 항원을 사용해 제작됨. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from cytoplasmic domain of SLC9A1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: SLC9A1.
Target Information
The Na⁺/H⁺ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by signals such as growth factors, mitogens, neurotransmitters, and tumor promoters.
Nhe-1 also acts as an anchor for actin filaments to maintain cortical cytoskeleton integrity through interactions with ERM proteins (ezrin, radixin, moesin).
It may play structural roles independent of ion exchange and is implicated in hypertension. At least two isoforms of Nhe-1 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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