
Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3764)
인간 ACE/CD143를 인식하는 마우스 단클론 항체. IHC, ELISA 등 다양한 응용에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, PBS 버퍼에 0.05% BSA와 sodium azide 포함. 4°C에서 보관, 동결 금지.
- 카탈로그번호
- 1636-MSM4-P0
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACE/3764 |
| Immunogen | Full-length recombinant human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme that catalyzes the conversion of angiotensin I into the physiologically active peptide angiotensin II. Angiotensin II acts as a potent vasopressor and aldosterone-stimulating peptide, regulating blood pressure and fluid-electrolyte balance. This enzyme plays a central role in the renin-angiotensin system. Variations in the presence or absence of a 287 bp Alu repeat element have been associated with circulating enzyme levels and cardiovascular conditions. Two major alternatively spliced variants encode the somatic and testicular isozymes, both active forms. Additional variants have been identified, though their full-length sequences are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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