Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3763)
인간 ACE/CD143 단백질을 인식하는 마우스 단클론 항체로, WB, IHC, ELISA 등에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 1 mg/mL 농도. 혈압 조절 관련 연구 및 레닌-안지오텐신 시스템 연구에 적합.
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- 1636-MSM3-P1ABX
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACE/3763 |
| Immunogen | Recombinant fragment (around aa 652–788) of human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into the physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance.
This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with circulating enzyme levels or cardiovascular pathophysiologies.
Two major alternatively spliced variants encode the somatic and testicular isozymes, both active forms. Several additional splice variants have been identified, though their full-length sequences remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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