Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3762)
Human ACE/CD143 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot, IHC, ELISA 등 다양한 응용에 적합합니다. Recombinant fragment(aa 652-788)를 면역원으로 사용하며, 단백질 A/G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | |
| ELISA | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ACE/3762 |
| Immunogen | Recombinant fragment (around aa 652–788) of human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide, angiotensin II. Angiotensin II acts as a potent vasopressor and aldosterone-stimulating peptide that regulates blood pressure and fluid-electrolyte balance. The enzyme plays a crucial role in the renin-angiotensin system. Studies have linked the presence or absence of a 287 bp Alu repeat element in this gene with circulating enzyme levels and cardiovascular pathophysiologies. Two major alternatively spliced variants encode the somatic and testicular forms, both enzymatically active. Additional splice variants have been identified but are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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