Thermo Fisher Scientific EpoR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 274-508 of human EPOR (NP_0001121) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EpoR,uniProtId:P19235-1,ncbiNodeId:9606,antigenRange:274-508,antigenLength:508,antigenImageFileName:PA5-91874_EpoR_P19235-1_Rabbit.svg,antigenImageFileNamePDP:PA5-91874_EpoR_P19235-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.16 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806314

Product Specific Information

Positive Samples: K-562, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein

Immunogen sequence: HRRALKQKIW PGIPSPESEF EGLFTTHKGN FQLWLYQNDG CLWWSPCTPF TEDPPASLEV LSERCWGTMQ AVEPGTDDEG PLLEPVGSEH AQDTYLVLDK WLLPRNPPSE DLPGPGGSVD IVAMDEGSEA SSCSSALASK PSPEGASAAS FEYTILDPSS QLLRPWTLCP ELPPTPPHLK YLYLVVSDSG ISTDYSSGDS QGAQGGLSDG PYSNPYENSL IPAAEPLPPS YVACS

Target Information

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.