Thermo Fisher Scientific HDAC9 Monoclonal Antibody (OTI5B8), TrueMAB
인간 HDAC9 단백질을 인식하는 mouse IgG1 단일클론 항체입니다. Western blot과 IHC(P)에서 검증되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific HDAC9 Monoclonal Antibody (OTI5B8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 181–460 of human HDAC9 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
DNA associates with histones and nuclear proteins to form chromatin, which undergoes remodeling through acetylation and deacetylation processes that regulate transcription.
Histone deacetylases (HDACs) 1–9 are involved in transcriptional silencing. HDAC9 and HDAC9a are alternatively spliced isoforms, both retaining catalytic activity and repressing myocyte enhancer-binding factor 2-mediated transcription.
HDAC9 and HDAC9a are expressed in brain, skeletal muscle, kidney, placenta, and pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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