Thermo Fisher Scientific HDAC9 Monoclonal Antibody (OTI7A5), TrueMAB
HDAC9 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 검증 완료. Human 시료에 반응하며, 동결건조 형태로 제공. PBS buffer(8% trehalose) 내 보존, -20°C 보관. 연구용으로 chromatin remodeling 및 histone 탈아세틸화 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HDAC9 Monoclonal Antibody (OTI7A5), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 181–460 of human HDAC9 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
In intact cells, DNA associates with histones and other nuclear proteins to form chromatin. Chromatin remodeling is essential for transcriptional regulation, with histone acetylation serving as a key mechanism. Acetylation of lysine residues in histone tails induces structural changes that enhance DNA accessibility to transcription factors.
Histone deacetylases (HDACs) counteract this process and are linked to transcriptional silencing. The HDAC family includes HDAC1–9. HDAC9 and its isoform HDAC9a differ by 132 amino acids but both retain catalytic activity and repress myocyte enhancer-binding factor 2-mediated transcription. HDAC9 and HDAC9a are expressed in brain, skeletal muscle, kidney, placenta, and pancreas.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.