
Thermo Fisher Scientific Phospho-Histone H2A (Thr121) Polyclonal Antibody
Phospho-Histone H2A (Thr121) 특이적 폴리클로날 항체로, 인산화된 H2A를 선택적으로 검출. Western blot 및 IHC(P)에서 검증됨. Rabbit IgG 기반, 액상 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM (Accession P0C0S8), corresponding to amino acid residues around phosphorylated Thr121. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816253 |
Product Specific Information
Antibody detects endogenous levels of Histone H2A only when phosphorylated at Threonine 121.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each core histone (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction. This gene encodes a histone H4 family member, is intronless, and its transcripts lack polyA tails but contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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